INSULIN RESISTANCE – THE MAIN PATHOPHYSIOLOGICAL FACTOR OF THE PATHOGENESIS OF TYPE 2 DIABETES

Abstract

This article analyzes the pathophysiological role of insulin resistance in the development of type 2 diabetes, its relationship with metabolic disorders, and its importance for public health. Insulin resistance is characterized by a decrease in the sensitivity of tissues to insulin. This condition leads to impaired glucose metabolism, chronic hyperglycemia, and the subsequent development of diabetic complications